From acclaimed mangaka Tsutomu Nihei, the creator and artist behind BLAME! and Knights of Sidonia, comes his newest Sci-Fi epic. Keisha and Titania continue to hunt down Regular Frames in order to speed along Etherow's recovery. As Kajiwan creates Regenerateds from those afflicted with Frame Disease, the Empire deploys new weapons in its fight against both Titania's party and the True Core Church. When the Emperor himself makes a surprise appearance, Titania takes a chance that alters the future...