This book covers recent developments in the implementation of a European collaboration for assessing cross-border toxicological threats. It discusses the European guidelines for the risk assessment and management of serious international public health dangers. It covers REACH (Registration, Evaluation, Authorisation & Restriction of Chemicals) directives and the work of the ASHT (Alerting System for Chemical Health Threats) project. It will be useful for to public health regulators, toxicologists, poisons centres, industrialists and COSHH (Control of Substances Hazardous to Health) specialists.