1. Introduction: What are the political challenges of COVID-19 in Latin America?Part I: The deniers 2. Brazilian response to Covid-19: polarization and conflict 3. Mexico in the face of Covid-19: in between actions and inefficiency 4. Nicaragua: denying the health crisis and the political crisis Part II: State Action During COVID-19 Pandemic 5. Managing the pandemic in Colombia: between the immediate response and the structural consequences 6. The Uruguayan's State's structure and the management of the pandemic Part III: Social Movements and pandemic 7. Solidarity during the Pandemic: Creative Recombinations in Social Movement Frames and Repertoires 8. Transformative events and collective action in Chile during the Covid pandemic Part IV: Public opinion and pandemic 9. Presidential approval during the Covid-19 pandemic in Argentina 10. Identity versus fear of death: political polarization under the Covid-19 pandemic in Brazil 11. Between pessimism and mistrust: Ecuadorian attitudes in the 2020 coronavirus pandemic 12. "For the sake of all, the Poor First" covid, mañaneras and the popularity of the mexican president 13. Conclusion: Comparing cases to understand the political challenges of COVID-19 in Latin America