Putting Knowledge to Work, explores the shifting power dynamics in research collaboration between donors in the Global North and recipients in the Global South; the difficult, yet mutually desired, research collaborations between Global North non-governmental organizations (NGOs) and Global North universities; and strategies devised by NGOs to create and use knowledge for influencing positive social change locally, as well as for improving themselves as organizations. It identifies and documents several inspiring practices to overcome specific challenges, drawing on select Canadian CSOs (CCSOs) own experiences, including universities, NGOs, and coalitions thereof. These vary in size, field of expertise, mandate, and geographic focus; yet, they all have been developing different approaches to tackling challenges identified by their community in Canada. It is the hope of all the contributors to this book that such positive deviations from mainstream practice will inspire others in tackling their own challenges, in order to remain significant players in international development.