This specially formulated collection features 3 reviews of current topics and key research in sweetpotato. The first chapter examines the origin and dispersal of sweetpotato, considers in vitro germplasm storage in sweetpotato genebanks, and looks at the importance of managing sweetpotato crop wild relatives (CWR). The chapter also considers the specific issues associated with sweetpotato germplasm, as well as the application of next-generation sequencing to sweetpotato and its CWR. The second chapter reviews the development and application of genetic transformation and trait improvement to sweetpotato, including the development of sweetpotato plants which are resistant to disease and abiotic stress, and sweetpotatoes with improved starch quality and higher anthocyanin content. The final chapter examines the nutritional contribution made by OFSP (orange-fleshed sweetpotato) in poor rural communities in Malawi, Ghana, Nigeria and Burkina Faso; sustainable breeding and seed systems; and effective commercialisation and marketing to benefit the communities concerned. This chapter includes detailed case studies from Ghana and Malawi.