Colombia, November 1993: a reconstructed old passenger train is carrying one hundred musicians, acrobats and artists on a daring adventure through the heart of a country soaked in violence. Leading this crusade of hope is Manu Chao with his band Mano Negra. Manu's father Ramon Chao is on board to chronicle the journey. As the papa of the train, he endures personal discomfort, internal strife, derailments, stowaways, disease, guerrillas and paramilitaries. When the train arrives in Aracataca, the real-life Macondo of One Hundred Years of Solitude, Mano Negra disintegrates, leaving Manu to pick up the pieces with those determined to see this once-in-a-lifetime adventure through to the end.