Name: Evolutionary conserved features of FG repeats that allow the formation of hydrogel-based perme-ability barriers with NPC-like properties (en Inglés)
Price: 174021.00 COP
Availability: InStock
Author: Schmidt, Hermann Broder
ISBN: 9783954044917

portada Evolutionary conserved features of FG repeats that allow the formation of hydrogel-based perme-ability barriers with NPC-like properties (en Inglés)

Formato

Libro Físico

Autor

Hermann Broder Schmidt

Editorial

Cuvillier

Idioma

Inglés

N° páginas

172

Encuadernación

Tapa Blanda

Dimensiones

21.0 x 14.8 x 0.9 cm

Peso

0.21 kg.

ISBN13

9783954044917

Categorías

Bioquímica

Evolutionary conserved features of FG repeats that allow the formation of hydrogel-based perme-ability barriers with NPC-like properties (en Inglés)

Hermann Broder Schmidt (Autor) · Cuvillier · Tapa Blanda

Libro Físico

$ 174.021

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Ahorras: $ 102.203

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Envío normal

Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "Evolutionary conserved features of FG repeats that allow the formation of hydrogel-based perme-ability barriers with NPC-like properties (en Inglés)"

Non-globular FG domains constitute the permeability barrier of nuclear pore complexes (NPCs), which control all macromolecular exchange between nucleus and cytoplasm. Whilst objects smaller than 30kDa can passively diffuse across this barrier, larger molecules need to be chaperoned by nuclear transport receptors (NTRs). However, the modus operandi and, inextricably linked, the exact physical nature of the NPC permeability barrier are still controversially discussed. Whereas so far, most studies exclusively focused on yeast or vertebrate FG domains, the ability of FG domains from different species to form selective barriers was explored here. Interestingly, all studied species contain 'cohesive' FG domains that interact with each other to form a characteristic (hydrogel) phase mimicking the permeability properties of NPCs.