Name: Neutrophilic Inflammation and Diseases: Pathophysiology, Biomarkers and Therapeutic Targets (en Inglés)
Price: 232319.00 COP
Availability: InStock
Author: Ramirez, Dario C. ; Mejiba, Sandra E. Gomez
ISBN: 9781952751387

portada Neutrophilic Inflammation and Diseases: Pathophysiology, Biomarkers and Therapeutic Targets (en Inglés)

Neutrophilic Inflammation and Diseases: Pathophysiology, Biomarkers and Therapeutic Targets (en Inglés)

Formato

Libro Físico

Autor

Dario C. Ramirez

Sandra E. Gomez Mejiba

Editorial

Eliva Press

Idioma

Inglés

N° páginas

180

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 1.0 cm

Peso

0.25 kg.

ISBN13

9781952751387

Categorías

Enfermedades y trastornos

Neutrophilic Inflammation and Diseases: Pathophysiology, Biomarkers and Therapeutic Targets (en Inglés)

Dario C. Ramirez (Autor) · Sandra E. Gomez Mejiba (Autor) · Eliva Press · Tapa Blanda

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Reseña del libro "Neutrophilic Inflammation and Diseases: Pathophysiology, Biomarkers and Therapeutic Targets (en Inglés)"

Endogenous (in the blood) or exogenous stressors can irritate tissues increasing adhesion and activation of neutrophils. This process is known as neutrophilic inflammation and includes the activation of neutrophils. This activation of neutrophils includes the activation of myeloperoxidase (MPO), NADPH oxide-reductase (NOX-2) and inducible nitric oxide synthase (iNOS) with generation of harmful neutrophil extracellular traps (NETs), and a broad range of reactive biochemical species. Oxidative modification can change the structure and function of macromolecules leading to tissue damage and diseases. NETs, MPO, NOX-2 and iNOS, as well as proteases and oxidized macromolecules are useful biomarkers ofdiseases as well as potential therapeutic targets. This book is focused in the latest information about the role of neutrophilic inflammation in the pathogenesis of acute and chronic diseases, as well as novel biomarkers and therapeutic targets. In silico, in vitro, ex-vivo and in vivo experimental studies are comprehensively discussed in light of the most currentinformation in this field.