Name: The Fungal Cell Wall Integrity Pathway (en Inglés)
Price: 331858.00 COP
Availability: InStock
Author: Molina, María ; Martín, Humberto
ISBN: 9783036569734

portada The Fungal Cell Wall Integrity Pathway (en Inglés)

Formato

Libro Físico

Editorial

Mdpi AG

Autor

Molina, María ; Martín, Humberto

Idioma

Inglés

N° páginas

392

Encuadernación

Tapa Dura

Dimensiones

24.4 x 17.0 x 3.0 cm

Peso

1.04 kg.

ISBN13

9783036569734

Categorías

Biología

The Fungal Cell Wall Integrity Pathway (en Inglés)

Molina, María ; Martín, Humberto (Autor) · Mdpi AG · Tapa Dura

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Reseña del libro "The Fungal Cell Wall Integrity Pathway (en Inglés)"

Adaptation to external changes is necessary for all cells to survive and thrive in diverse environments. Key to these responses are the MAPK-mediated signaling pathways, intracellular communication routes that sense stimuli at the cell surface, and are ubiquitous in all eukaryotic organisms. In the case of fungi, MAPKs mediate essential processes, such as adaptation to environmental stresses, morphology regulation, or developmental processes. First studied in the early nineties in Saccharomyces cerevisiae, the fungal cell wall integrity (CWI) pathway has proven to be a central MAPK-mediated signaling cascade conserved in the fungal kingdom. Cells need to sense cell wall-perturbing conditions and mount the appropriate salvage response. Understanding this CWI pathway-mediated compensatory mechanism is key for the development of cell wall-targeted antifungal therapies. Moreover, its functional roles go beyond the maintenance of this essential structure, reaching many other physiological aspects that have major implications in development or virulence.In this Special Issue, expert researchers in this relevant subject have contributed with seven reviews and eleven original articles to advance our understanding of the CWI pathway by covering different structural, regulatory, and functional aspects in distinct yeasts and filamentous fungi.