Name: Evaluation of Gingival Collagen in Rats Immunosuppressed With Csa: Evaluation of Gingival Collagen in Experimental Periodontitis in Rats Immunosuppressed With csa (en Inglés)
Price: 160407.00 COP
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Author: Jéssica Cristiane Oliveira Costa
ISBN: 9786207606856

portada Evaluation of Gingival Collagen in Rats Immunosuppressed With Csa: Evaluation of Gingival Collagen in Experimental Periodontitis in Rats Immunosuppressed With csa (en Inglés)

Evaluation of Gingival Collagen in Rats Immunosuppressed With Csa: Evaluation of Gingival Collagen in Experimental Periodontitis in Rats Immunosuppressed With csa (en Inglés)

Formato

Libro Físico

Editorial

Our Knowledge Publishing

Autor

Jéssica Cristiane Oliveira Costa

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

ISBN13

9786207606856

Evaluation of Gingival Collagen in Rats Immunosuppressed With Csa: Evaluation of Gingival Collagen in Experimental Periodontitis in Rats Immunosuppressed With csa (en Inglés)

Jéssica Cristiane Oliveira Costa (Autor) · Our Knowledge Publishing · Tapa Blanda

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Reseña del libro "Evaluation of Gingival Collagen in Rats Immunosuppressed With Csa: Evaluation of Gingival Collagen in Experimental Periodontitis in Rats Immunosuppressed With csa (en Inglés)"

Cyclosporine A (CsA) is an immunosuppressant drug used mainly in transplant patients and can have the adverse effect of causing gingival hyperplasia. Some studies have shown that this increase may be due to a change in fibroblast metabolism and connective tissue homeostasis, characterizing this condition as a risk for periodontal disease. The aim of this study was to compare gingival connective tissue in experimental periodontitis in rats immunosuppressed with CsA. Twenty-eight male rats (Wistar) were used, 14 treated with daily doses of 10mg/kg of CsA and 14 treated with NaCl. After 60 days, a ligature was inserted around the 2nd upper right molar, maintained for 7 days and then 14 days to induce experimental periodontitis (T), with the contralateral molar as a control (C). After sacrificing the animals, the jaws were processed for histological analysis and 5 semi-serial sections per specimen were stained with picrosirious to quantify the collagen.