Name: Mutations in Human Genetic Disease (en Inglés)
Price: 591065.00 COP
Availability: InStock
Author: Cooper, David ; Chen, Jian-Min
ISBN: 9789535107903

portada Mutations in Human Genetic Disease (en Inglés)

Mutations in Human Genetic Disease (en Inglés)

Formato

Libro Físico

Editorial

Intechopen

Autor

Cooper, David ; Chen, Jian-Min

Idioma

Inglés

N° páginas

308

Encuadernación

Tapa Dura

Dimensiones

24.4 x 17.0 x 1.9 cm

Peso

0.69 kg.

ISBN13

9789535107903

Categorías

Genética médica

Mutations in Human Genetic Disease (en Inglés)

Cooper, David ; Chen, Jian-Min (Autor) · Intechopen · Tapa Dura

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Reseña del libro "Mutations in Human Genetic Disease (en Inglés)"

Different types of mutation can vary in size, from structural variants to single base-pair substitutions, but what they all have in common is that their nature, size and location are often determined either by specific characteristics of the local DNA sequence environment or by higher order features of the genomic architecture. The genomes of higher organisms are now known to contain "pervasive architectural flaws" in that certain DNA sequences are inherently mutation prone by virtue of their base composition, sequence repetitivity and/or epigenetic modification. In this volume, a number of different authors from diverse backgrounds describe how the nature, location and frequency of different types of mutation causing inherited disease are shaped in large part, and often in remarkably predictable ways, by the local DNA sequence environment.