Name: prominin-1 (cd133): new insights on stem & cancer stem cell biology (en Inglés)
Price: 833308.00 COP
Availability: InStock
Author: Corbeil, Denis
ISBN: 9781461458937

portada prominin-1 (cd133): new insights on stem & cancer stem cell biology (en Inglés)

Formato

Libro Físico

Ilustrado por

Denis Corbeil

Editorial

Springer

Autor

Corbeil, Denis

Año

2012

Idioma

Inglés

N° páginas

252

Encuadernación

Tapa Dura

Dimensiones

23.4 x 15.7 x 2.0 cm

Peso

0.59 kg.

ISBN

1461458935

ISBN13

9781461458937

Categorías

Oncología
Bioquímica
Biología celular | citología

prominin-1 (cd133): new insights on stem & cancer stem cell biology (en Inglés)

Denis Corbeil (Ilustrado por) · Springer · Tapa Dura

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "prominin-1 (cd133): new insights on stem & cancer stem cell biology (en Inglés)"

Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine.