Name: Protein Biomarkers: Discovery and Applications in Clinical Diagnostics (en Inglés)
Price: 815518.00 COP
Availability: InStock
Author: Singh Sumit Kumar,Chandra Pranjal
ISBN: 9789819750443

portada Protein Biomarkers: Discovery and Applications in Clinical Diagnostics (en Inglés)

Protein Biomarkers: Discovery and Applications in Clinical Diagnostics (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Singh Sumit Kumar,Chandra Pranjal

Idioma

Inglés

N° páginas

395

Encuadernación

Tapa Dura

ISBN13

9789819750443

N° edición

2024th

Protein Biomarkers: Discovery and Applications in Clinical Diagnostics (en Inglés)

Singh Sumit Kumar,Chandra Pranjal (Autor) · Springer · Tapa Dura

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Reseña del libro "Protein Biomarkers: Discovery and Applications in Clinical Diagnostics (en Inglés)"

This book comprehensively reviews the fundamentals of biomarker discovery using mass-spectrometry-based proteomic and glycoproteomic methods. It also provides case studies of proteomic and glycoproteomic molecular signatures to illustrate the design and use of various mass spectrometry modes such as selected reaction monitoring (SRM), parallel reaction monitoring (PRM), and sequential window acquisition of all theoretical fragment ion spectra mass spectrometry (SWATH-MS). In turn, the book presents the challenges of the proteomic methods in biomarker discovery and approaches for overcoming these challenges by extending the performance by improving the sensitivity, throughput, and selectivity of the method. It also addresses the bottleneck of deriving useful biological interpretations from large multi-dimensional datasets emanating from these experiments by discussing data analysis pipelines and appropriate statistical analysis. Finally, a detailed discussion on the design, characterization, and application of protein/glycoprotein-based biosensors for clinical diagnostics is discussed. The book is intended to serve as a reliable resource for the students and researchers working in the area of biomarker discovery and validation using mass spectrometry-based methods and their subsequent applications for biosensor design.