Cell Biology (Life Sciences)
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Ribosome-Inactivating Proteins: Ricin and Related Proteins
Stirpe, Fiorenzo ; Lappi, Douglas (Autor)
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Wiley-Blackwell
· Tapa Dura
Ribosome-Inactivating Proteins: Ricin and Related Proteins - Stirpe, Fiorenzo ; Lappi, Douglas
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Reseña del libro "Ribosome-Inactivating Proteins: Ricin and Related Proteins"
This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.
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