Name: Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)
SKU: 67312770
Price: 250756.00 COP
Availability: InStock
Author: Mahdi Karimi;Parham Sahandi Zangabad;Amir Ghasemi
ISBN: 9780750328074

portada Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)

Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)

Formato

Libro Físico

Editorial

Morgan & Claypool Publishers

Autor

Mahdi Karimi;Parham Sahandi Zangabad;Amir Ghasemi

Año

2015

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

25.4x17.8x0.4 cm

ISBN13

9780750328074

Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)

Mahdi Karimi;Parham Sahandi Zangabad;Amir Ghasemi (Autor) · Morgan & Claypool Publishers · Tapa Blanda

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Reseña del libro "Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)"

The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo: this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to externally applied stimuli that usually involve the application of physical energy. This physical energy can be applied from outside the body and can either cause cargo release, or can activate the nanostructure to be cytotoxic, or both. The stimuli covered include light of various wavelengths (ultraviolet, visible or infrared), temperature (increased or decreased), magnetic fields (used to externally manipulate nanostructures and to activate them), ultrasound, and electrical and mechanical forces. Finally, we discuss the issue of nanotoxicology and the future scope of the field.