Name: The Chemical Biology of Long Noncoding Rnas (en Inglés)
Price: 636869.00 COP
Availability: InStock
Author: Jurga, Stefan ; Barciszewski, Jan
ISBN: 9783030447458

portada The Chemical Biology of Long Noncoding Rnas (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Jurga, Stefan ; Barciszewski, Jan

Idioma

Inglés

N° páginas

545

Encuadernación

Tapa Blanda

Dimensiones

23.4 x 15.6 x 2.9 cm

Peso

0.77 kg.

ISBN13

9783030447458

Categorías

Equipamiento y técnicas médicas
Génetica médica
Bioquímica

The Chemical Biology of Long Noncoding Rnas (en Inglés)

Jurga, Stefan ; Barciszewski, Jan (Autor) · Springer · Tapa Blanda

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Reseña del libro "The Chemical Biology of Long Noncoding Rnas (en Inglés)"

This book offers a comprehensive and detailed overview of various aspects of long non-coding RNAs. It discusses their emerging significance in molecular medicine, ranging from human cancers to cardiovascular and metabolic diseases. Transcriptomic studies have demonstrated that the majority of genomes found in complex organisms are expressed in highly dynamic and cell-specific patterns, producing huge numbers of intergenic, antisense and intronic long non-protein-coding RNAs (lncRNAs). Thousands of lncRNAs have been identified, and unlike mRNA, they have no protein-coding capacity. A large repertoire of ncRNAs, actively transcribed from the mammalian genome, control diverse cellular processes, both in terms of development and diseases, through a variety of gene regulatory mechanisms. IncRNAs have emerged as a new paradigm in epigenetic regulation of the genome. Given its scope, the book will be of particular interest to molecular, chemical, cell and developmental biologists, as well as specialists in translational medicine involved in disease-oriented research. It also offers a valuable resource for in silico experts seeking a deeper understanding of lncRNA expression and function through computational analysis of the NGS data.